UNIVERSITAS AIRLANGGA



Detail Article

Veterinaria Medika

ISSN 1979-1305

Vol. 8 / No. 2 / Published : 2015-07

Order : 10, and page :179 - 186

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Original Article :

Protective effect of binahong leaf extract [anredera cordifolia (ten.) steenis] to renal histopathological of rat (rattus norvegicus) induced with borax (na2b4o710h2o)

Author :

  1. Waridah Ilahiah Basari*1
  2. Djoko Galijono*2
  3. Arimbi*3
  1. Mahasiswa Fakultas Kedokteran Hewan
  2. Dosen Fakultas Kedokteran Hewan
  3. Dosen Fakultas Kedokteran Hewan

Abstract :

The purpose of this study was to evaluate the protective effect of binahong leave extract [Anredera cordifolia (Ten.) Steenis] on renal histopathological damage of rat (Rattus norvegicus strain wistar) that caused by borax. 24 male rats (Rattus norvegicus strain Wistar) aged 3 month with body weight (BW) 200 g were used as animals model. These animals were divided into six groups (P0-, P0+Bor, P0+Bin, P1, P2, dan P3). P0- were sterile aquadest 0,5 ml/rats/day + CMC Na liquid 1%, P0+Bor were CMC Na liquid 1% + borax 157 mg/rats/day, P0+Bin were 50mg/kg BW + steril aquadest P1 were binahong extract 50mg/kg BW + borax 157 mg/rats/day, P2 were binahong extract 100mg/kg BW + borax 157 mg/rats/day, and P3 were binahong extract 200mg/kg BW + borax 157 mg/rats/day. This research has been conducted for 14 days to determine the protective effects of binahong extract on the renal damage that caused by borax toxicity. The data were compared using Kruskal-Wallis test and Mann-Whitney test. The result showed that borax have significantly caused haemorrhage, degeneration, necrosis and glomerulonephritis on renal histopathology and binahong extract didn’t give significant protective effect on renal histopathology (p<0,05).

Keyword :

Binahong, protective effect, borax, disodium tetraborate decahydrate, Renal histopathology,


References :

Nielsen, FH,(1994) Biochemical and physiologic consequences of boron deprivation in humans. 102: 59-63 : Environ Health Perspect





Archive Article

Cover Media Content

Volume : 8 / No. : 2 / Pub. : 2015-07
  1. The effect of acupuncture on sodium, potassium, and chloride blood plasma in thoroughbred horse after exercise
  2. The effects of insulin transferin selenium (its) supplementation on embryo freezing media at morula stage towards the percentage of embryonic development at blastula stage
  3. The liver histopathology of mice (mus musculus) cause exposure carbofuran insectiside
  4. Effect of mangosteen rind extract (garcinia mangostana l.) to necrosis alveolar type ii cell of lungonpregnant mice (mus musculus)exposured by cigarette smoke
  5. Histopathological appearance of gastrointestinal tract iv instar mosquito larvae of aedes aegypti after dipping with active compounds of permot leaf extract (passiflora foetida linn.) and its potential as bioinsecticide
  6. The effects of differences in the duration of the thawing of frozen semen to sperm quality peranakan ettawa goat
  7. The seminal plasma protein of cow sustain quality of beans goat spermatozoa after equilibration in freezing process
  8. The potential of garlic (allium sativum) infuse to caecum of broilers histopathology infected by escherichia coli
  9. The effectiveness of giving haemopoetic stem cells in the pregnant mice (mus musculus) exposed to plumbum towards the decreasing number of necrocis cells and expression of caspase-3 in placenta
  10. Protective effect of binahong leaf extract [anredera cordifolia (ten.) steenis] to renal histopathological of rat (rattus norvegicus) induced with borax (na2b4o710h2o)
  11. Effect of antibacterial traditional apple vinegar and apple vinegar products on the growth of staphylococcus aureus in vitro
  12. The effect of mangosteen peel extract (garcinia mangostana l.) to the number of placental trophoblast cells in mice (mus musculus) exposure to cigarette smoke
  13. Analysis of humoral immune response (igg) in rabbit immunized with proteins of leucocytozoon caulleryi
  14. Isolation of methicillin-resistant staphylococcus aureus (mrsa) in dog nasal swab with oxacillin screen agar confirmation test
  15. Effect of prostaglandin f2α, pregnant mare serum gonadotropin, and a combination of pregnant mare serum gonadotropin and human chorionic gonadotropin on pregnancy rates and litter size of mice
  16. Through the provision of drinking water multiprobio against performan broiler chicken production

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